Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Becker, JC.
Tumor-educated myeloid cells: impact the micro- and macroenvironment.
Exp Dermatol. 2014; 23(3):157-158
Doi: 10.1111/exd.12241
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Becker Jürgen Christian
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Immune escape mechanisms of cancers include some of the mechanisms normally used for immune homeostasis, particular those preventing autoimmunity; one of these is the polarisation of myeloid cells. Thereby, tumors, i.e. the cancerous and stromal cells, also condition distant sites like spleen and bone marrow via soluble factors and membrane vesicles such as exosomes in order to create a tumor-educated macroenvironment. Albeit these mechanisms are currently in the focus of (tumor-)immunologic research, the first evidence had been published almost 40 years ago. One of these early reports will be discussed here. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Cell Communication - immunology
- Cytoplasmic Vesicles - metabolism
- Exosomes - metabolism
- Humans -
- Lymphocytes - immunology
- Membrane Proteins - metabolism
- Find related publications in this database (Keywords)
- immune escape mechanism
- myeloid-derived suppressor cell
- tumor associated macrophage