Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Wolf, EM; Plieschnegger, W; Geppert, M; Wigginghaus, B; Höss, GM; Eherer, A; Schneider, NI; Hauer, A; Rehak, P; Vieth, M; Langner, C.
Changing prevalence patterns in endoscopic and histological diagnosis of gastritis? Data from a cross-sectional Central European multicentre study.
Dig Liver Dis. 2014; 46(5):412-418
Doi: 10.1016/j.dld.2013.12.017
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Langner Cord
- Co-Autor*innen der Med Uni Graz
- Eherer Andreas
- Hauer Almuthe
- Rehak Peter
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- Abstract:
- Traditionally, Helicobacter infection is considered to be the most common cause of gastritis. In the cross-sectional Central European histoGERD trial, we assessed the prevalence of different types of gastritis, correlating histological and endoscopic diagnoses. A total of 1123 individuals participated in an observational multicentre study. Endoscopists classified individuals as positive or negative for gastritis and rendered the putative cause. Pathologists evaluated biopsy specimens based upon the Updated Sydney System. Histological diagnosis of gastritis was made in 639 (56.9%) participants. In all, 210 (18.7%) individuals were diagnosed with Helicobacter gastritis, 215 (19.1%) with post Helicobacter gastritis, 234 (20.8%) with reactive gastropathy, 26 (2.3%) with autoimmune gastritis, and 6 (0.5%) with focally enhanced gastritis related to Crohn's disease. In 46 out of 639 (7.2%) individuals diagnosed with gastritis, combinations of different histological subtypes were noted the most common being reactive gastropathy and post Helicobacter gastritis. Endoscopic diagnosis of gastritis was made in 534 (47.6%) individuals. Reactive gastropathy was more common than active Helicobacter gastritis, and the majority of cases attributable to Helicobacter infection were no longer ongoing, i.e. post Helicobacter gastritis. Agreement between histological and endoscopic diagnoses was better in reactive gastropathy than in Helicobacter gastritis. Copyright © 2014 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Aged, 80 and over -
- Aged, 80 and over - epidemiology
- Autoimmune Diseases - epidemiology Autoimmune Diseases - pathology
- Crohn Disease - complications
- Cross-Sectional Studies -
- Endoscopy, Gastrointestinal -
- Female -
- Gastritis - epidemiology Gastritis - etiology Gastritis - pathology
- Gastritis - epidemiology
- Helicobacter Infections - complications Helicobacter Infections - drug therapy Helicobacter Infections - epidemiology
- Helicobacter pylori -
- Humans -
- Male -
- Metaplasia - pathology
- Middle Aged -
- Prevalence -
- Proton Pump Inhibitors - therapeutic use
- Pyloric Antrum - pathology
- Young Adult -
- Find related publications in this database (Keywords)
- Epidemiology
- Gastropathy
- Helicobacter gastritis
- Intestinal metaplasia
- Reflux gastritis