Medizinische Universität Graz - Research portal

Go directly to the nagivation.
Go directly to the content.

Navigation/Search

Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Low, N; Heijne, JC; Herzog, SA; Althaus, CL.
Reinfection by untreated partners of people treated for Chlamydia trachomatis and Neisseria gonorrhoeae: mathematical modelling study.
Sex Transm Infect. 2014; 90(3):254-256 Doi: 10.1136/sextrans-2013-051279
Web of Science PubMed FullText FullText_MUG

Co-authors Med Uni Graz: Herzog Sereina Annik
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: Reinfection after treatment for Chlamydia trachomatis or Neisseria gonorrhoeae reduces the effect of control interventions. We explored the impact of delays in treatment of current partners on the expected probability of reinfection of index cases using a mathematical model. We used previously reported parameter distributions to calculate the probability that index cases would be reinfected by their untreated partners. We then assumed different delays between index case and partner treatment to calculate the probabilities of reinfection. In the absence of partner treatment, the medians of the expected reinfection probabilities are 19.4% (IQR 9.2-31.6%) for C trachomatis and 12.5% (IQR 5.6-22.2%) for N gonorrhoeae. If all current partners receive treatment 3 days after the index case, the expected reinfection probabilities are 4.2% (IQR 2.1-6.9%) for C trachomatis and 5.5% (IQR 2.6-9.5%) for N gonorrhoeae. Quicker partner referral and treatment can substantially reduce reinfection rates for C trachomatis and N gonorrhoeae by untreated partners. The formula we used to calculate reinfection rates can be used to inform the design of randomised controlled trials of novel partner notification technologies like accelerated partner therapy.
Find related publications in this database (using NLM MeSH Indexing): Adolescent -; Adult -; Chlamydia Infections - epidemiology; Chlamydia trachomatis - isolation & purification; Contact Tracing -; Female -; Gonorrhea - epidemiology; Humans -; Male -; Models, Theoretical -; Neisseria gonorrhoeae - isolation & purification; Referral and Consultation -; Sexual Partners -; Time Factors -