Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Haas, A; Walzl, M; Eckhardt, M; Walzl, B; Faulborn, J; Feigl, B.
Influence of a single HELP application on hemorheology and retinal hemodynamics.
Ophthalmologica. 1996; 210(3):171-174
Doi: 10.1159/000310701
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Haas Anton
- Co-Autor*innen der Med Uni Graz
- Feigl Beatrix
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- Abstract:
- The heparin-induced extracorporeal low-density lipoprotein precipitation (HELP) eliminates selectively fibrinogen, total cholesterol, low-density lipoproteins (LDL) and triglycerides and improves hemorheology. We investigated the hemodynamic changes in 10 patients without ocular diseases performing a video fluorescein angiography after a single HELP procedure measuring the arm-retina time (ART) and the arteriovenous passage time (AVP). Laboratory parameters such as fibrinogen, cholesterol, LDL, triglycerides, red cell transit time, plasma and whole-blood viscosity were determined and retinal circulation was measured immediately before and after the HELP application. All of the laboratory parameters were lowered significantly. The ART was unaffected by the HELP procedure; however, there was a significant AVP reduction from 2.41 +/- 0.49 to 1.97 +/- 0.47 (p < 0.005). These results support the hemorheological and hemodynamic efficiency of the HELP system in microcirculatory diseases.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Anticoagulants - administration and dosage
- Blood Flow Velocity - administration and dosage
- Blood Viscosity - physiology
- Cholesterol - blood
- Female - blood
- Fibrinogen - analysis
- Fluorescein Angiography - analysis
- Fundus Oculi - analysis
- Hearing Disorders - blood
- Heparin - administration and dosage
- Humans - administration and dosage
- Lipoproteins - blood
- Male - blood
- Middle Aged - blood
- Precipitation - blood
- Retinal Vessels - physiology
- Triglycerides - blood
- Find related publications in this database (Keywords)
- Heparin-Induced Extracorporeal Low-Density Lipoprotein Precipitation (Help)
- Fibrinogen
- Hemorheology
- Retinal Hemodynamics
- Arteriovenous Passage Time