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Hirsch, FW; Sattler, B; Sorge, I; Kurch, L; Viehweger, A; Ritter, L; Werner, P; Jochimsen, T; Barthel, H; Bierbach, U; Till, H; Sabri, O; Kluge, R.
PET/MR in children. Initial clinical experience in paediatric oncology using an integrated PET/MR scanner.
Pediatr Radiol. 2013; 43(7):860-875
Doi: 10.1007/s00247-012-2570-4
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- Co-authors Med Uni Graz
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Till Holger
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- Abstract:
- Use of PET/MR in children has not previously been reported, to the best of our knowledge. Children with systemic malignancies may benefit from the reduced radiation exposure offered by PET/MR. We report our initial experience with PET/MR hybrid imaging and our current established sequence protocol after 21 PET/MR studies in 15 children with multifocal malignant diseases. The effective dose of a PET/MR scan was only about 20% that of the equivalent PET/CT examination. Simultaneous acquisition of PET and MR data combines the advantages of the two previously separate modalities. Furthermore, the technique also enables whole-body diffusion-weighted imaging (DWI) and statements to be made about the biological cellularity and nuclear/cytoplasmic ratio of tumours. Combined PET/MR saves time and resources. One disadvantage of PET/MR is that in order to have an effect, a significantly longer examination time is needed than with PET/CT. In our initial experience, PET/MR has turned out to be an unexpectedly stable and reliable hybrid imaging modality, which generates a complementary diagnostic study of great additional value.
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Adolescent -
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Child -
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Child, Preschool -
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Equipment Design -
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Equipment Failure Analysis -
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Female -
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Humans -
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Infant -
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Magnetic Resonance Imaging - instrumentation
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Male -
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Multimodal Imaging - instrumentation
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Neoplasms - diagnosis
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Pilot Projects -
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Positron-Emission Tomography - instrumentation
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Radiation Dosage -
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Radiation Protection - instrumentation
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Radiometry -
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Reproducibility of Results -
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Sensitivity and Specificity -
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Children
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PET/MR
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MR/PET
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Oncology
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Hybrid imaging