Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Obermoser, G; Pfausler, BE; Linder, DM; Sepp, NT.
Scleroderma en coup de sabre with central nervous system and ophthalmologic involvement: treatment of ocular symptoms with interferon gamma.
J Am Acad Dermatol. 2003; 49(3):543-546
Doi: 10.1067/S0190-9622(03)00901-0
(- Case Report)
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Linder Michael Dennis
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- Abstract:
- Scleroderma en coup de sabre, a variant of localized scleroderma, is a disorder of unknown origin characterized by fibrosis of connective tissue. Rare complications of scleroderma en coup de sabre are orbital and intracerebral involvement. We describe a patient with scleroderma en coup de sabre in whom intracerebral and orbital lesions developed after 2 decades of disease duration. Clinically, she had epilepsy, impaired vision, and retro-ocular pain of the affected eye. A 12-month course of interferon-gamma stopped progression of visual symptoms caused by orbital fibrous tissue. To our knowledge, this is the first patient with scleroderma en coup de sabre complicated by orbital involvement who was successfully treated with interferon-gamma.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Brain Diseases - complications Brain Diseases - diagnosis Brain Diseases - drug therapy
- Drug Administration Schedule -
- Epilepsy - complications Epilepsy - diagnosis Epilepsy - drug therapy
- Eye Diseases - complications Eye Diseases - diagnosis Eye Diseases - drug therapy
- Female -
- Follow-Up Studies -
- Humans -
- Interferon-gamma - therapeutic use
- Long-Term Care -
- Magnetic Resonance Imaging -
- Risk Assessment -
- Scleroderma, Localized - complications Scleroderma, Localized - diagnosis Scleroderma, Localized - drug therapy
- Severity of Illness Index -
- Treatment Outcome -
- Visual Acuity -