Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Apalla, Z; Lallas, A; Tzellos, T; Sidiropoulos, T; Lefaki, I; Trakatelli, M; Sotiriou, E; Lazaridou, E; Evangelou, G; Patsatsi, A; Kyrgidis, A; Stratigos, A; Zalaudek, I; Argenziano, G; Ioannides, D.
Applicability of dermoscopy for evaluation of patients' response to nonablative therapies for the treatment of superficial basal cell carcinoma.
Br J Dermatol. 2014; 170(4):809-815
Doi: 10.1111/bjd.12749
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Zalaudek Iris
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Applicability of dermoscopy in evaluation of outcome and monitoring of superficial basal cell carcinoma (sBCC) after nonablative therapies has not been sufficiently assessed. Certain dermoscopic criteria, namely pigmented structures, ulceration and arborizing vessels, have been suggested to predict the presence of residual disease [residual disease-associated dermoscopic criteria (RDADC)]. We aimed to assess this hypothesis. Lesions exhibiting RDADC 3 months after treatment were biopsied and in the case of histopathological confirmation were excised. Lesions characterized by white/red structureless areas, superficial fine telangiectasias, or lacking any dermoscopic criterion, were monitored for 12 months. At the 3-month evaluation, one or more of the RDADC were detected in 25/98 (25·5%) sBCCs, in which histology confirmed tumour persistence. In 45 (61·6%) of the 73 remaining lesions, dermoscopy showed white/red structureless areas and/or superficial fine telangiectasias. Twenty-eight lacked any dermoscopic criterion of sBCC. The two latter groups entered follow-up. In total, disease recurred in 13 (17·8%) of the 73 lesions. RDADC accurately predict residual disease. Absence of dermoscopic criteria of sBCC safely predicts complete histopathological clearance. Detection of white/red structureless areas and/or superficial fine telangiectasias warrants close monitoring to recognize early recurrence. © 2013 British Association of Dermatologists.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Aminolevulinic Acid - administration & dosage
- Aminolevulinic Acid - analogs & derivatives
- Aminoquinolines - administration & dosage
- Antineoplastic Combined Chemotherapy Protocols - therapeutic use
- Carcinoma, Basal Cell - drug therapy
- Carcinoma, Basal Cell - pathology
- Dermoscopy - methods
- Humans -
- Imiquimod -
- Male -
- Middle Aged -
- Neoplasm, Residual - pathology
- Photochemotherapy - methods
- Photosensitizing Agents - administration & dosage
- Skin Neoplasms - drug therapy
- Skin Neoplasms - pathology
- Treatment Outcome -