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Naldi, L; Chatenoud, L; Linder, D; Belloni Fortina, A; Peserico, A; Virgili, AR; Bruni, PL; Ingordo, V; Lo Scocco, G; Solaroli, C; Schena, D; Barba, A; Di Landro, A; Pezzarossa, E; Arcangeli, F; Gianni, C; Betti, R; Carli, P; Farris, A; Barabino, GF; La Vecchia, C.
Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian case-control study.
J Invest Dermatol. 2005; 125(1): 61-67.
Doi: 10.1111/j.0022-202X.2005.23681.x
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- Co-Autor*innen der Med Uni Graz
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Linder Michael Dennis
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- Abstract:
- We conducted a case-control study to analyse the association of psoriasis of recent onset with smoking habits, body mass index (BMI) and stressful life events. Cases (n=560; median age 38) were patients with a first diagnosis of psoriasis and a history of skin manifestations of no longer than two years after the reported disease onset. Patients with a new diagnosis of skin diseases other than psoriasis (n=690; median age 36) were selected as controls. The risk of psoriasis was higher in ex- and current smokers than in never-smokers, the relative risk estimates (OR) being 1.9 for ex-smokers and 1.7 for smokers. Smoking was strongly associated with pustular lesions (32 patients, OR=5.3 for smokers). The frequency of psoriasis varied significantly in relation to a family history of psoriasis in first degree relatives, BMI (OR=1.6 and 1.9 for over weighted, BMI 26-29, and obese, BMI >/= 30, respectively) and stressful life event score (compared to the lower index quartile, the OR being 2.2 for index values >/=115). Risk estimates, when taking into consideration the combined effect of these factors with smoking habits, were consistent with a multiplicative model of risk combination with no significant statistical interaction.
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Adult -
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Body Mass Index -
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Case-Control Studies -
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Female -
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Humans -
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Humans -
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Male -
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Middle Aged -
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Psoriasis - etiology
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Risk Factors -
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Smoking - adverse effects
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Stress, Psychological - complications
- Find related publications in this database (Keywords)
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body mass index
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case-control study
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family history
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life events
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psoriasis
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risk factors
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smoking habits