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SHR Neuro Cancer Cardio Lipid Metab Microb
Pichler, G; Binder, C; Avian, A; Beckenbach, E; Schmölzer, GM; Urlesberger, B.
Reference ranges for regional cerebral tissue oxygen saturation and fractional oxygen extraction in neonates during immediate transition after birth.
J Pediatr. 2013; 163(6):1558-1563
Doi: 10.1016/j.jpeds.2013.07.007
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Pichler Gerhard
- Co-authors Med Uni Graz
- Avian Alexander
- Binder-Heschl Corinna
- Schmölzer Georg
- Urlesberger Berndt
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- Abstract:
- Objective To define reference ranges for regional cerebral tissue oxygen saturation (crSO(2)) and regional cerebral fractional tissue oxygen extraction (cFTOE) during the first 15 minutes after birth in neonates requiring no medical support. Study design The crSO(2) was measured using near infrared spectroscopy (Invos 5100 cerebral/somatic oximeter monitor; Somanetics Corp, Troy, Michigan) during the first 15 minutes after birth for term and preterm neonates. The near infrared spectroscopy sensor was placed on the left forehead. Peripheral oxygen saturation and heart rate were continuously measured by pulse oximetry, and cFTOE was calculated. Neonates were excluded if they required any medical support. Results A total of 381 neonates were included: 82 term neonates after vaginal delivery, 272 term neonates after cesarean delivery, and 27 preterm neonates after cesarean delivery. In all neonates, median (10th-90th percentiles) crSO(2) was 41% (23-64) at 2 minutes, 68% (45-85) at 5 minutes, 79% (65-90) at 10 minutes, and 77% (63-89) at 15 minutes of age. In all neonates, median (10th-90th percentiles) cFTOE was 33% (11-70) at 2 minutes, 21% (6-45) at 5 minutes, 15% (5-31) at 10 minutes, and 18% (7-34) at 15 minutes of age. Conclusion We report reference ranges of crSO(2) and cFTOE in neonates requiring no medical support during transition immediately after birth. The use of cerebral oxygenation monitoring and use of these reference ranges in neonates during transition may help to guide oxygen delivery and avoid cerebral hypo-oxygenation and hyperoxygenation.
- Find related publications in this database (using NLM MeSH Indexing)
- Brain - metabolism
- Humans -
- Infant, Newborn -
- Monitoring, Physiologic - methods
- Oxygen - analysis
- Prospective Studies -
- Reference Values -
- Spectroscopy, Near-Infrared -
- Time Factors -