Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Lasta, M; Palkovits, S; Boltz, A; Schmidl, D; Kaya, S; Cherecheanu, AP; Garhöfer, G; Schmetterer, L.
Reproducibility of retinal vessel oxygen saturation measurements in healthy young subjects.
Acta Ophthalmol. 2012; 90(8): e616-e620.
Doi: 10.1111/j.1755-3768.2012.02513.x
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- Co-Autor*innen der Med Uni Graz
- Palkovits Stefan
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- Abstract:
- Purpose: An adequate oxygenation and perfusion is essential for the function of the inner retina. Recently, several techniques for the measurement of retinal oxygen saturation became available. We set out to evaluate reproducibility of the measurements using a modified Retinal Vessel Analyzer. Methods: A total of 20 healthy female and male subjects aged between 18 and 35 years (22.9 +/- 3.9; mean +/- SD) were included. The measurement of retinal oxygen saturation with the retinal oximeter employed in this study is based on optical reflectometry using the different absorption characteristics of oxygenated and deoxygenated haemoglobin. The intraclass correlation coefficients and the coefficients of variation (CV) for testretest, short-term as well as day-to-day measurements were calculated. Results: The intraclass correlation coefficients were between 0.91 and 0.94 for retinal branch arteries and between 0.84 and 0.88 for retinal branch veins. In retinal arteries, we calculated a testretest CV of 3.24 +/- 3.18% for oxygen saturation measurements. In retinal veins, data were slightly less reproducible with a CV of 4.92 +/- 3.57%. Short-term reproducibility of both measurement cycles on each study day was in the same range (CV in retinal arteries: 2.91 +/- 2.42% and CV in retinal veins: 4.76 +/- 3.14%). The day-to-day coefficient of variation was slightly higher (CV in retinal arteries: 3.97 +/- 2.87% and CV in retinal veins: 6.18 +/- 3.36%). Conclusion: The reproducibility of haemoglobin oxygen saturation measurements using the retinal oximeter is acceptable. Further studies on the validity of the obtained results are, however, required.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Blood Pressure - physiology
- Female -
- Heart Rate - physiology
- Hemoglobins - metabolism
- Humans -
- Male -
- Oximetry - methods
- Oxygen - blood
- Oxygen Consumption - physiology
- Plethysmography -
- Reproducibility of Results -
- Retinal Artery - physiology
- Retinal Vein - physiology
- Young Adult -
- Find related publications in this database (Keywords)
- haemoglobin
- oxygen saturation
- retina
- vessels