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Flick, H; Drescher, M; Prattes, J; Tovilo, K; Kessler, HH; Vander, K; Seeber, K; Palfner, M; Raggam, RB; Avian, A; Krause, R; Hoenigl, M.
Predictors of H1N1 influenza in the emergency department: proposition for a modified H1N1 case definition.
Clin Microbiol Infect. 2014; 20(2):O105-O108
Doi: 10.1111/1469-0691.12352
[OPEN ACCESS]
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
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Flick Holger
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Hönigl Martin
- Co-Autor*innen der Med Uni Graz
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Avian Alexander
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Kessler Harald
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Krause Robert
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Palfner Michael
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Prattes Jürgen
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Raggam Reinhard Bernd
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- Abstract:
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Reliable and rapid diagnosis of influenza A H1N1 is essential to initiate appropriate antiviral therapy and preventive measures. We analysed the differences in clinical presentation and laboratory parameters between emergency department patients with PCR-confirmed H1N1 influenza infection (n = 199) and those with PCR-negative influenza-like illness (ILI; n = 252). Cough, wheezing, leucopenia, eosinopenia and a lower C-reactive protein remained significant predictors of H1N1 influenza. Proposed combinations of clinical symptoms with simple laboratory parameters (e.g. reported or measured fever and either cough or leucocytes <8.5 × 10(9) /L) were clearly superior to currently used official ILI case definitions that use clinical criteria alone.
© 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.
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Adolescent -
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Adult -
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Aged -
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Aged, 80 and over -
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Child -
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Child, Preschool -
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Clinical Laboratory Techniques - methods
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Clinical Medicine - methods
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Emergency Medicine - methods
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Emergency Service, Hospital -
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Female -
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Humans -
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Infant -
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Infant, Newborn -
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Influenza A Virus, H1N1 Subtype - isolation & purification
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Influenza, Human - diagnosis Influenza, Human - pathology Influenza, Human - virology
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Young Adult -
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Berlin
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clinical presentation
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H1N1
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influenza A
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laboratory values
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PCR