Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Koestenberger, M; Ravekes, W; Nagel, B; Avian, A; Heinzl, B; Fritsch, P; Sorantin, E; Cvirn, G; Rehak, T; Gamillscheg, A.
Longitudinal systolic ventricular interaction in pediatric and young adult patients with TOF: a cardiac magnetic resonance and M-mode echocardiographic study.
Int J Cardiovasc Imaging. 2013; 29(8):1707-1715
Doi: 10.1007/s10554-013-0261-3
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Koestenberger Martin
- Co-Autor*innen der Med Uni Graz
- Avian Alexander
- Cvirn Gerhard
- Fritsch Peter
- Gamillscheg Andreas
- Nagel Bert Hermann Philipp
- Rehak Thomas
- Sorantin Erich
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- Abstract:
- Aim of this prospective study was to evaluate longitudinal systolic left ventricular (LV)-right ventricular (RV) interaction using M-mode compared to magnetic resonance imaging (MRI) data in 146 pediatric and adults with operated tetralogy of Fallot (TOF). We determined biventricular measures of longitudinal M-mode echocardiography [i.e., tricuspid annular plane systolic excursion (TAPSE); the mitral annular plane systolic excursion (MAPSE)] compared to longitudinal function parameters using MRI. M-mode data were compared to established normal z-score values. We found a good correlation between MAPSE and LVEF values (r = 0.788; p < 0.001). Correlations between MRI derived MAPSE and M-mode guided MAPSE (r = 0.879, p < 0.001), and between MRI derived TAPSE and M-mode guided TAPSE were significant (r = 0.780, p < 0.001). While the LVEF was normal in patients with a normal RVEF, the LVEF was decreased in patients with significantly reduced RVEF. Patients with a significantly dilated RV (RVEDVi > 150 ml/m(2)) showed a significantly reduced mean MAPSE of 1.30 ± 0.26 cm. LV longitudinal function decreases below -2 SD of normal MAPSE z-score values after a mean of 22 postoperative years. Our data confirm progressive adverse RV-LV interaction in the long-term follow-up of TOF. We show that simple M-mode measurement of the longitudinal LV function (i.e. MAPSE) is a sufficient surrogate for estimation of LVEF. Therefore determination of the MAPSE is a helpful additional tool for LV systolic function assessment late after TOF repair.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Age Factors -
- Cardiac Surgical Procedures - adverse effects
- Case-Control Studies -
- Child -
- Child, Preschool -
- Echocardiography -
- Female -
- Humans -
- Hypertrophy, Right Ventricular - etiology
- Infant -
- Infant, Newborn -
- Longitudinal Studies -
- Magnetic Resonance Imaging, Cine -
- Male -
- Mitral Valve - physiopathology
- Predictive Value of Tests -
- Prospective Studies -
- Stroke Volume -
- Systole -
- Tetralogy of Fallot - physiopathology
- Time Factors -
- Treatment Outcome -
- Tricuspid Valve - physiopathology
- Ventricular Dysfunction, Left - etiology
- Ventricular Dysfunction, Right - etiology
- Ventricular Function, Left -
- Ventricular Function, Right -
- Young Adult -
- Find related publications in this database (Keywords)
- Mitral annular plane systolic excursion
- Magnetic resonance imaging
- M-mode
- Tricuspid annular plane systolic excursion
- Tetralogy of Fallot