Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Prietl, B; Treiber, G; Pieber, TR; Amrein, K.
Vitamin D and immune function.
Nutrients. 2013; 5(7):2502-2521
Doi: 10.3390/nu5072502
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- Leading authors Med Uni Graz
- Amrein Karin
- Prietl Barbara
- Co-authors Med Uni Graz
- Pieber Thomas
- Treiber Gerlies
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- Abstract:
- Vitamin D metabolizing enzymes and vitamin D receptors are present in many cell types including various immune cells such as antigen-presenting-cells, T cells, B cells and monocytes. In vitro data show that, in addition to modulating innate immune cells, vitamin D also promotes a more tolerogenic immunological status. In vivo data from animals and from human vitamin D supplementation studies have shown beneficial effects of vitamin D on immune function, in particular in the context of autoimmunity. In this review, currently available data are summarized to give an overview of the effects of vitamin D on the immune system in general and on the regulation of inflammatory responses, as well as regulatory mechanisms connected to autoimmune diseases particularly in type 1 diabetes mellitus.
- Find related publications in this database (using NLM MeSH Indexing)
- Adaptive Immunity - drug effects
- Animals -
- Autoimmune Diseases - immunology
- Diabetes Mellitus, Type 1 - immunology
- Dietary Supplements -
- Humans -
- Immune System - drug effects
- Immunity, Innate - drug effects
- Nutritional Status -
- Randomized Controlled Trials as Topic -
- Receptors, Calcitriol - immunology
- Seasons -
- Vitamin D - administration & dosage
- Find related publications in this database (Keywords)
- vitamin D
- autoimmunity
- immune cells
- adaptive immunity
- innate immunity
- cholecalciferol
- calcitriol
- 25(OH)D