Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Di Stefani, A; Massone, C; Soyer, HP; Zalaudek, I; Argenziano, G; Arzberger, E; Lozzi, GP; Chimenti, S; Hofmann-Wellenhof, R.
Benign dermoscopic features in melanoma.
J Eur Acad Dermatol Venereol. 2014; 28(6):799-804
Doi: 10.1111/jdv.12192
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Arzberger Edith Johanna
- Hofmann-Wellenhof Rainer
- Massone Cesare
- Soyer Hans Peter
- Zalaudek Iris
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- Abstract:
- Various dermoscopic features are usually associated with benign melanocytic lesions. Our objective was to determine frequency and extension of benign dermoscopic features (BDF) in melanoma. Retrospective review of dermoscopic images of a consecutive series of 516 histopathologically proven melanomas collected in 6 years in Graz. Correlation of BDF with mean Breslow thickness, with presence/absence of associated benign nevus component and with the pre-operative clinico-dermoscopic diagnosis, as reported on the original histopathologic reports. In addition to melanoma specific criteria, 42% of melanomas showed BDF. In 12.3% cases, the benign features occupied more than the half of the lesion. The BDF typical pigment network, homogeneous pattern and regular globules/cobblestone pattern had the highest frequency. BDF were associated with relatively thinner melanomas (mean Breslow thickness of 0.51 mm). The presence of BDF was observed in 67.1% of histopathologically documented nevus-associated melanoma and in 35.7% of melanoma de novo. A pre-operative clinico-dermoscopic diagnosis of melanoma was achieved in only 54.1% of cases displaying BDF. A significant proportion of melanomas may exhibit BDF. Clinicians should be aware of the presence of BDF in melanoma as possible diagnostic pitfall. © 2013 European Academy of Dermatology and Venereology.
- Find related publications in this database (using NLM MeSH Indexing)
- Dermoscopy -
- Humans -
- Melanoma - pathology
- Retrospective Studies -
- Skin Neoplasms - pathology