Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
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Klonowski, W; Pierzchalski, M; Stepien, P; Stepien, R; Sedivy, R; Ahammer, H; .
Application of Higuchi's fractal dimension in analysis of images of Anal Intraepithelial Neoplasia.
CHAOS SOLITON FRACTAL. 2013; 48: 54-60.
Doi: 10.1016/j.chaos.2013.01.004
Web of Science
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- Co-Autor*innen der Med Uni Graz
- Ahammer Helmut
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- Abstract:
- To reduce computational complexity, 2-D images of tumors are firstly preprocessed following our method to form two 1-D sequences, called horizontal and vertical landscapes, and then their fractal dimension is estimated using Higuchi's fractal dimension. We validate application of this method for grading Anal Intraepithelial Neoplasia (AIN) tumors using 120 images of histological slices graded by an experienced pathologist. The method is easy and quick and we demonstrate that it may be successfully applied for differentiation between AIN stages. It can easily be adapted to other histological specimen. Of course, like any other semiautomatic method it may support the pathologist's decision. (C) 2013 Elsevier Ltd. All rights reserved.