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SHR Neuro Cancer Cardio Lipid Metab Microb
Breschan, C; Jost, R; Krumpholz, R; Schaumberger, F; Stettner, H; Marhofer, P; Likar, R.
A prospective study comparing the analgesic efficacy of levobupivacaine, ropivacaine and bupivacaine in pediatric patients undergoing caudal blockade.
Paediatr Anaesth. 2005; 15(4):301-6
Doi: 10.1111/j.1460-9592.2004.01443.x
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PubMed
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- Leading authors Med Uni Graz
- Breschan Christian
- Co-authors Med Uni Graz
- Likar Rudolf
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- Abstract:
- BACKGROUND: The aim of our study was to compare postoperative analgesic efficacy, analgesic duration and motor blockade of levobupivacaine, ropivacaine and bupivacaine administered caudally in equal concentrations to children undergoing elective minor surgery. METHODS: In the study, 182 children, aged 1-7 years, undergoing either inguinal hernia repair or orchidopexy, were randomly allocated to one of the three groups. They received via a caudal extradural either 1 ml x kg(-1) levobupivacaine 0.2% (Group L) or 1 ml x kg(-1) ropivacaine 0.2% (Group R) or 1 ml x kg(-1) bupivacaine 0.2% (Group B). RESULTS: No statistically significant difference was noted in age, weight, duration of the operation or level of the caudal block between the groups. The onset of analgesia was significantly later after levobupivacaine. Postoperative pain scoring evaluated with Children's and Infant's Postoperative Pain Scale observational scale showed no statistical difference between groups. Median postoperative analgesia was 5.75 h (SEMed: +/- 0.65) in Group L, 5.7 h (SEMed: +/- 0.8) in Group R and 5.35 h (SEMed: +/- 1.3) in Group B the difference being statistically nonsignificant. CONCLUSIONS: The degree of motor block was significantly less after ropivacaine and levobupivacaine during the first 2 h postoperatively.
- Find related publications in this database (using NLM MeSH Indexing)
- Amides - adverse effects
- Anesthesia, Caudal - adverse effects
- Anesthetics, Local - adverse effects
- Bupivacaine - adverse effects, chemistry
- Child - administration & dosage
- Child, Preschool - administration & dosage
- Digestive System Surgical Procedures - administration & dosage
- Female - administration & dosage
- Hemodynamics - drug effects
- Hernia, Inguinal - surgery
- Humans - administration & dosage
- Infant - administration & dosage
- Male - administration & dosage
- Motor Neurons - drug effects
- Nerve Block - adverse effects
- Oxygen - blood
- Pain Measurement - administration & dosage
- Pain, Postoperative - epidemiology
- Prospective Studies - administration & dosage
- Ropivacaine - administration & dosage
- Stereoisomerism - administration & dosage
- Testis - surgery
- Find related publications in this database (Keywords)
- caudal extradural
- analgesia
- levobupivacaine
- ropivacaine
- bupivacaine