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Breschan, C; Krumpholz, R; Likar, R; Kraschl, R; Schalk, HV.
Can a dose of 2microg.kg(-1) caudal clonidine cause respiratory depression in neonates?
Paediatr Anaesth. 1999; 9(1):81-83 Doi: 10.1046/j.1460-9592.1999.00277.x (- Case Report)
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Leading authors Med Uni Graz
Breschan Christian
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Abstract:
A case of multiple life-threatening postoperative apnoeas in a term neonate undergoing inguinal herniorrhaphy and orchidopexy who received light inhalation anaesthesia combined with caudal block with 1 ml.kg-1 ropivacaine 0.2% plus 2 microg.kg-1 clonidine is reported. The patient showed no apparent risk factors for postanaesthetic apnoea. Oxycardiorespirography five days after surgery only showed minor abnormalities. Clonidine though administered caudally in the usual dose of 2 microg.kg-1 appeared to be the most likely cause for postanaesthetic apnoea in this neonate.
Find related publications in this database (using NLM MeSH Indexing)
Adrenergic alpha-Agonists - administration and dosage Adrenergic alpha-Agonists - adverse effects
Amides - administration and dosage
Anesthesia, Caudal - adverse effects
Anesthesia, Inhalation -
Anesthetics, Local - administration and dosage
Apnea - chemically induced
Bradycardia - chemically induced
Clonidine - administration and dosage Clonidine - adverse effects
Hernia, Inguinal - surgery
Humans -
Infant, Newborn -
Male -
Oxygen - blood
Postoperative Complications - chemically induced
Respiration - drug effects
Risk Factors -
Testis - surgery

Find related publications in this database (Keywords)
postoperative apnoea
neonate preterm infant
clonidine
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