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Eser, A; Thalhammer, F; Burghuber, F; Högenauer, C; Stockenhuber, F; Wenisch, C; Widhalm, K; Reinisch, W.
Probiotics for the prevention of antibiotic-induced diarrhea].
Z Gastroenterol. 2012; 50(10):1089-1095
Doi: 10.1055/s-0032-1312950
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
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Hoegenauer Christoph
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- Abstract:
- Between 5 and 49% of patients treated with antibiotics suffer from diarrhoea. Principally all microbial agents can cause diarrhoea, especially oral agents like cephalosporines, clindamycin, broad-spectrum penicillins, and quinolones of the 3 rd and 4th generation. Manifestations of antibiotic-associated diarrhoea range from mild self-limiting forms to severe life-threatening courses. The potentially most severe form of antibiotic-associated diarrhoea is caused by Clostridium diffcile accounting for approx. 25 % of antibiotic-associated diarrhoea. In the past two decades a broad spectrum of different probiotic strains has been evaluated for the primary prevention of antibiotic-associated diarrhoea in children and adults. Based on their efficacy and clinical data, different levels of evidence and recommendations are emerging on the preventive use of probiotics in antibiotic-associated diarrhoea.
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Adult -
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Anti-Bacterial Agents - adverse effects
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Child -
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Diarrhea - drug therapy
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Humans -
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Probiotics - therapeutic use
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Treatment Outcome -
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probiotics
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antibiotic-associated diarrhoea
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Clostridium difficile