Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Cosentino, M; Breda, A; Sanguedolce, F; Landman, J; Stolzenburg, JU; Verze, P; Rassweiler, J; Van Poppel, H; Klingler, HC; Janetschek, G; Celia, A; Kim, FJ; Thalmann, G; Nagele, U; Mogorovich, A; Bolenz, C; Knoll, T; Porpiglia, F; Alvarez-Maestro, M; Francesca, F; Deho, F; Eggener, S; Abbou, C; Meng, MV; Aron, M; Laguna, P; Mladenov, D; D'Addessi, A; Bove, P; Schiavina, R; De Cobelli, O; Merseburger, AS; Dalpiaz, O; D'Ancona, FC; Polascik, TJ; Muschter, R; Leppert, TJ; Villavicencio, H.
The use of mannitol in partial and live donor nephrectomy: an international survey.
World J Urol. 2013; 31(4):977-982
Doi: 10.1007/s00345-012-1003-1
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Dalpiaz Orietta
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- Abstract:
- Animal studies have shown the potential benefits of mannitol as renoprotective during warm ischemia; it may have antioxidant and anti-inflammatory properties and is sometimes used during partial nephrectomy (PN) and live donor nephrectomy (LDN). Despite this, a prospective study on mannitol has never been performed. The aim of this study is to document patterns of mannitol use during PN and LDN. A survey on the use of mannitol during PN and LDN was sent to 92 high surgical volume urological centers. Questions included use of mannitol, indications for use, physician responsible for administration, dosage, timing and other renoprotective measures. Mannitol was used in 78 and 64 % of centers performing PN and LDN, respectively. The indication for use was as antioxidant (21 %), as diuretic (5 %) and as a combination of the two (74 %). For PN, the most common dosages were 12.5 g (30 %) and 25 g (49 %). For LDN, the most common doses were 12.5 g (36.3 %) and 25 g (63.7 %). Overall, 83 % of centers utilized mannitol, and two (percent or centers??) utilized furosemide for renoprotection. A large majority of high-volume centers performing PN and LDN use mannitol for renoprotection. Since there are no data proving its value nor standardized indication and usage, this survey may provide information for a randomized prospective study.
- Find related publications in this database (using NLM MeSH Indexing)
- Anti-Inflammatory Agents - administration & dosage
- Antioxidants - administration & dosage
- Dose-Response Relationship, Drug -
- Health Care Surveys -
- Humans -
- Internationality -
- Kidney - drug effects
- Kidney Transplantation - methods
- Living Donors -
- Mannitol - administration & dosage
- Nephrectomy - methods
- Prospective Studies -
- Questionnaires -
- Time Factors -
- Find related publications in this database (Keywords)
- Mannitol
- Live donor nephrectomy
- Partial nephrectomy
- Renoprotective agent
- Diuretics