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SHR Neuro Cancer Cardio Lipid Metab Microb
Horwath-Winter, J; Vidic, B; Schwantzer, G; Schmut, O.
Early changes in corneal sensation, ocular surface integrity, and tear-film function after laser-assisted subepithelial keratectomy.
J CATARACT REFRACT SURG. 2004; 30(11): 2316-2321.
Doi: 10.1016/j.jcrs.2004.03.042
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Horwath-Winter Jutta
- Co-authors Med Uni Graz
- Schmut Otto
- Schwantzer Gerold
- Vidic Bertram
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- Abstract:
- PURPOSE: To investigate the changes in corneal sensation, ocular surface integrity, and tear-film function after laser-assisted subepithelial keratectomy (LASEK). SETTING: Department of Ophthalmology, University of Graz, Graz, Austria. METHODS: Laser-assisted subepithelial keratectomy was performed in 21 consecutive patients (37 myopic eyes). The patients were observed for subjective complaints of dry eye, corneal sensation, tear-film breakup time (BUT), Schirmer test without local anesthesia, and fluorescein and lissamin-green staining preoperatively and 1 week and 1, 3, and 6 months postoperatively. RESULTS: The subjective score for dry-eye symptoms was not statistically significantly higher after the procedure. Corneal sensation was reduced up to 1 month after LASEK (P<.05). There were obvious decreases in BUT at 1 week and 1 month (P<.01) and no significant changes in Schirmer test results. In fluorescein staining of the cornea, dots were more concentrated at 1 week (P<.05). In lissamin-green staining, no significant changes were found at any follow-up examination. CONCLUSIONS: Laser-assisted subepithelial keratectomy induced a short-term reduction in corneal sensation and affected the ocular surface and tear film slightly. Epithelial flap repositioning in LASEK may have a positive influence on tear-film and ocular-surface factors.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Cornea - physiology
- Dry Eye Syndromes - physiopathology
- Epithelium, Corneal - physiopathology
- Female - physiopathology
- Fluorescent Dyes - diagnostic use
- Humans - diagnostic use
- Keratectomy, Subepithelial, Laser-Assisted - diagnostic use
- Male - diagnostic use
- Middle Aged - diagnostic use
- Myopia - surgery
- Prospective Studies - surgery
- Sensation - physiology
- Surgical Flaps - physiology
- Tears - physiology