Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Riccabona, M; .
Application of a second-generation US contrast agent in infants and children-a European questionnaire-based survey.
PEDIAT RADIOL. 2012; 42(12): 1471-1480.
Doi: 10.1007/s00247-012-2472-5
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- Führende Autor*innen der Med Uni Graz
- Riccabona Michael
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- Abstract:
- No US contrast agent (US-CA) is currently licensed for use in children. To survey the off-label use in children of a second-generation US-CA. Questionnaires were e-mailed to European paediatric radiologists, who were asked about their experience with the second-generation US-CA SonovueA (R) (Bracco, Milan, Italy). Number of examinations per indication and adverse effects were recorded. Examinations were categorised by intravenous or intracavitary use of US-CA. Out of 146 respondents, 88 stated that they did not perform contrast-enhanced US in children, but 36 of these (44%) would appreciate paediatric approval. Forty-five centres reported 5,079 examinations in children (age mean: 2.9 years; range: birth-18 years, M/F: 1/ 2.8). The majority (4,131 [81%] in 29 centres) were intravesical applications. The minority (948 [19%] in 30 centres) were intravenous applications. No adverse effects had been recorded from intravesical use. Six minor adverse effects (skin reaction, unusual taste, hyperventilation) had been recorded after five intravenous studies (0.52%). Responses suggest a favourable safety profile of this second-generation US-CA in children. It also demonstrates a demand for such US-CA from paediatric radiologists.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Child -
- Child, Preschool -
- Contrast Media -
- Drug Toxicity - epidemiology
- Drug Toxicity - epidemiology
- Female -
- Humans -
- Incidence -
- Infant -
- Male -
- Off-Label Use - statistics & numerical data
- Pediatrics - statistics & numerical data
- Physician's Practice Patterns - statistics & numerical data
- Questionnaires -
- Radiology - statistics & numerical data
- Risk Factors -
- Ultrasonography - utilization
- Find related publications in this database (Keywords)
- Contrast-enhanced ultrasound
- Child
- Voiding urosonography