Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schroeder, AS; Huss, K; Blaschek, A; Koerte, IK; Zeycan, B; Roser, T; Langhagen, T; Schwerin, A; Berweck, S; Reilich, P; Schaefer, J; Straube, A; Heinen, F.
Ten-year follow-up in a case series of integrative botulinum toxin intervention in adolescents with chronic daily headache and associated muscle pain.
Neuropediatrics. 2012; 43(6):339-345
Doi: 10.1055/s-0032-1329612
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Schwerin-Nagel Anette
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- Abstract:
- Introduction A total of 83% of children report headache during a 6-month period. The estimated 1-year prevalence of chronic daily headache (CDH) in children is at least 1 to 2%. Muscle pain is associated with headache severity and chronicity. Muscle pain can be associated with active muscular trigger points, a functional concept still remaining a controversy. An integrated approach including bio-behavioral management is accepted as standard treatment but does not provide sufficient pain relief in all patients. Objective We report the individual clinical course of five adolescents with treatment-refractory CDH associated with focal muscle pain. We describe a concept of short-term integrative intervention including botulinum toxin (StiBo) in a personalized ANDquot;follow the referred pain patternANDquot; injection regimen with the focus on long-term follow-up. Results StiBo showed short-term efficacy on headache frequency and severity. In the long-term follow-up, CDH was not existent in any of the patients. Conclusion The treatment may have enabled the patients to draw attention away from a repeated circle of muscle-triggered pain and withdrawal of daily activities toward self-driven activities, thereby potentially preventing the development of further chronification. To prove this hypothesis, a prospective, placebo-controlled study in young adolescents with CDH should be initiated including objective outcome parameters on muscular level.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Botulinum Toxins - therapeutic use
- Child -
- Follow-Up Studies -
- Headache Disorders - complications
- Humans -
- Musculoskeletal Pain - complications
- Pain Measurement -
- Severity of Illness Index -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- chronic daily headache
- migraine
- tension-type headache
- muscle pain
- botulinum toxin type A
- BoNT/A