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Eller, K; Kniepeiss, D; Rosenkranz, AR.
Preoperative risk evaluation: where is the limit for recipients of a pancreatic graft?
Curr Opin Organ Transplant. 2013; 18(1):97-101
Doi: 10.1097/MOT.0b013e32835c9666
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- Führende Autor*innen der Med Uni Graz
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Eller Kathrin
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Rosenkranz Alexander
- Co-Autor*innen der Med Uni Graz
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Kniepeiss Daniela
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- Abstract:
- Purpose review Pancreas transplantation is an accepted treatment strategy that can result in normalization of blood glucose, but this must be weighed against the risks of a surgical procedure and subsequent immunosuppression. To improve the risk/benefit ratio, pancreas transplantation is typically performed in end-stage renal disease patients who are undergoing simultaneous kidney transplantation or who previously received a renal transplant and are obligated to the use of immunosuppressive medications. As diabetic patients are at high risk for the development of cardiovascular disease, intensive evaluation before transplantation is necessary to minimize the perioperative and postoperative risk. Recent findings The field of pancreas transplantation has been limited by a lack of randomized controlled trials not only on the procedure of transplantation itself, but also on the preoperative evaluation of the patients. The data regarding pretransplant evaluation are scarce including its usefulness of tumor screening and cardiovascular evaluation, as well as its effectiveness. Summary Evaluation for pancreas transplantation is an important issue to minimize the risk of the patients for perioperative and postoperative complications. This is especially important in transplant recipients with a diabetic background, who are by definition 'high-risk patients' for transplantation.
- Find related publications in this database (using NLM MeSH Indexing)
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Cardiovascular Diseases - surgery
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Combined Modality Therapy - methods
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Diabetes Mellitus - surgery
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Humans -
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Immunosuppressive Agents - adverse effects
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Kidney Failure, Chronic - complications Kidney Failure, Chronic - surgery
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Kidney Transplantation - methods
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Obesity - complications
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Pancreas Transplantation - contraindications Pancreas Transplantation - methods
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Postoperative Complications - prevention & control
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Preoperative Care -
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Risk Assessment -
- Find related publications in this database (Keywords)
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pancreas transplantation
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preoperative risk evaluation
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simultaneous kidney pancreas transplantation