Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Wolf, EM; Högenauer, C; Asslaber, M; Langner, C.
Inflammatory esophageal polyp with bizarre stromal cells: possible diagnostic pitfall].
Pathologe. 2013; 34(2):159-161
Doi: 10.1007/s00292-012-1715-4
(- Case Report)
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Langner Cord
- Co-Autor*innen der Med Uni Graz
- Asslaber Martin
- Hoegenauer Christoph
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- Abstract:
- In the gastrointestinal tract an accurate diagnosis of tumor-like lesions can be challenging. In patients with reflux disease regenerative hyperplasia of esophageal squamous epithelium may show marked pleomorphism and atypia thereby simulating malignancy. Bizarre stromal cells are another diagnostic pitfall. We present the case of a 46-year-old patient with symptoms of reflux disease who was diagnosed with a benign inflammatory polyp at the distal end of the esophagus. Histology revealed bizarre cells within the stroma of the polyp characterized by nuclear hyperchromatism and enlargement. Mitoses were not observed. The atypical cells were positive for vimentin. The Ki67/MIB-1 proliferation rate was low. The morphology and etiology of bizarre stromal cells, including helpful features for differential diagnosis are thoroughly discussed.
- Find related publications in this database (using NLM MeSH Indexing)
- Biopsy -
- Cell Proliferation -
- Diagnosis, Differential -
- Esophageal Neoplasms - diagnosis Esophageal Neoplasms - pathology Esophageal Neoplasms - surgery
- Esophagitis - diagnosis Esophagitis - pathology Esophagitis - surgery
- Female -
- Gastroesophageal Reflux - diagnosis Gastroesophageal Reflux - pathology Gastroesophageal Reflux - surgery
- Gastroscopy -
- Humans -
- Ki-67 Antigen - analysis
- Middle Aged -
- Polyps - diagnosis Polyps - pathology Polyps - surgery
- Stromal Cells - pathology
- Tumor Markers, Biological - analysis
- Vimentin - analysis
- Find related publications in this database (Keywords)
- Esophagus
- Bizarre stromal cells
- Pseudoneoplastic lesion
- Immunohistochemistry
- Inflammatory polyp