Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Vogt, M; Lehnert, T; Till, H; Rolle, U; .
Evaluation of different modes of combined therapy in children with monosymptomatic nocturnal enuresis.
BJU Int. 2010; 105(10):1456-1459
Doi: 10.1111/j.1464-410X.2009.08872.x
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- Co-Autor*innen der Med Uni Graz
- Till Holger
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- Abstract:
- OBJECTIVE To evaluate the efficacy of different modes of combined therapy in children with monosymptomatic nocturnal enuresis (MNE). PATIENTS AND METHODS A randomized prospective study was performed to compare the order of two types of combined therapy in children with MNE. Group A was treated with primary desmopressin treatment that was combined with alarm treatment after 3 months, while group B was treated with primary alarm treatment that was combined with desmopressin after 3 months. RESULTS Within a period of 18 months, 43 previously untreated children fulfilled the inclusion criteria. Thirteen children achieved dryness after initial monotherapy or discontinued the study. Group A consisted of 16 children and group B of 14 children. After the standardized treatment course of 6 months, 11/16 children in group A and 11/14 children in group B became dry (ANDlt; 3 wet nights/month). Altogether, 22/30 (73%) children were dry after combined treatment, consisting of 12/18 boys and 10/12 girls. Of the children with a normal maximum voided volume, 79% (19/24) achieved dryness, whereas only three of six children with small maximum voided volumes became dry. In all, 13/19 (68%) children with nocturnal polyuria and nine of 11 without nocturnal polyuria became dry. Only one child relapsed (group A). CONCLUSIONS Combined therapy proved effective in children with MNE after 6 months, with no statistically significant differences between the two different orders of treatment.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Antidiuretic Agents - therapeutic use
- Behavior Therapy - methods
- Child -
- Child, Preschool -
- Combined Modality Therapy -
- Deamino Arginine Vasopressin - therapeutic use
- Female -
- Humans -
- Male -
- Nocturnal Enuresis - therapy
- Prospective Studies -
- Find related publications in this database (Keywords)
- enuresis
- alarm therapy
- desmopressin
- combined therapy