Medizinische Universität Graz - Research portal
Selected Publication:
Till, H; Muensterer, O; Graubner, U.
Laparoscopic adnexectomy of a persistent ovarian tumor in a girl with acute lymphoblastic leukemia relapse
Pediatr Hematol Oncol. 2003; 20(5):417-420
Doi: 10.1080/713842350
(- Case Report)
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- Leading authors Med Uni Graz
- Till Holger
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- Abstract:
- The management of children with acute lymphoblastic leukemia (ALL) relapse and an ovarian tumor remains controversial. The authors report about a 4-year-old girl who developed a late bone marrow and cutaneous relapse of her pre-B-cell ALL and revealed an enlargement of her left ovary (4 x 3 x 2 cm). Chemotherapy (ALL-REZ-BFM pilot-protocol 2002) achieved effective remission, but the ovarian mass depicted no regression. Laparoscopic adnexectomy was performed and the tumor could be extracted in a specimen-bag through a 12-mm umbilical incision. Histology detected no viable lymphoblasts, but a fibrotic enlargement due to previous cellular infiltration. The authors conclude that in children with ALL relapse and an ovarian tumor, malignant infiltration as well as local response to chemotherapy can be judged only by surgical excision and histopathologic examination. Laparoscopic oophoradnexectomy is a valuable management option in these children.
- Find related publications in this database (using NLM MeSH Indexing)
- Adnexa Uteri - surgery
- Antineoplastic Combined Chemotherapy Protocols - therapeutic use
- Bone Marrow Examination -
- Bone Marrow Neoplasms - pathology
- Child, Preschool -
- Female -
- Gynecologic Surgical Procedures - methods
- Humans -
- Laparoscopy -
- Ovarian Neoplasms - secondary Ovarian Neoplasms - surgery
- Ovariectomy - methods
- Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Precursor Cell Lymphoblastic Leukemia-Lymphoma - surgery
- Recurrence -
- Skin Neoplasms - pathology
- Treatment Outcome -
- Find related publications in this database (Keywords)
- acute lymphoblastic leukemia
- adnexectomy
- childhood
- laparoscopy
- ovary
- tumor