Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Muensterer, OJ; Klis, VJ; Till, H; von Schweinitz, D; Simbruner, G.
Effects on the maternofetal unit of the rabbit model after substitution of the amniotic fluid with perfluorocarbons
FETAL DIAGN THER. 2005; 20(5): 359-365.
Doi: 10.1159/000086813
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- Co-Autor*innen der Med Uni Graz
- Till Holger
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- Abstract:
- Objectives: Exchanging amniotic fluid (AF) with perfluorocarbon (PFC) may serve as a medium for fetoscopic surgery. This study evaluates the distribution and physiologic effects of intraamniotic PFC as a medium for fetoscopy. Methods: Fetuses of 17 pregnant rabbits underwent either exchange of the AF with PFC, electrolyte solution (ES), or control. The quality of vision during fetoscopy was assessed in AF and PFC. After 6 h, we determined the distribution of PFC in the maternofetal unit. Results: Quality of vision during fetoscopy was better in PFC than with AF. There was no difference in fetal survival between the study groups. PFC was demonstrated on X-ray in the pharynx of 4 fetuses, and the esophagus in 1. Conclusions: PFC provided an ideal medium for fetoscopy without fetal compromise. Copyright (c) 2005 S. Karger AG, Basel.
- Find related publications in this database (using NLM MeSH Indexing)
- Amniotic Fluid -
- Animals -
- Electrolytes - pharmacology
- Esophagus - radiography
- Female -
- Fetoscopy - methods Fetoscopy - mortality
- Fluorocarbons - pharmacology
- Heart Rate, Fetal -
- Lung - radiography
- Models, Animal -
- Pharynx - radiography
- Pregnancy -
- Rabbits -
- Find related publications in this database (Keywords)
- perfluorocarbon
- fetal endoscopic surgery
- amniotic fluid
- rabbit model