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Pakisch, B; Urban, C; Slavc, I; Poier, E; Stücklschweiger, G; Oberbauer, R; Mokry, M; Poschauko, J; Hammer, J; Leitner, H.
Hyperfractionated radiotherapy and polychemotherapy in brain stem tumors in children.
Childs Nerv Syst. 1992; 8(4):215-218 Doi: 10.1007/BF00262849
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Co-authors Med Uni Graz
Hackl Arnulf
Mokry Michael
Urban Ernst-Christian
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Abstract:
Between October 1989 and January 1991 five children with brain stem tumors were treated with sequential chemo- and radiotherapy. The polychemotherapy consisted of procarbazine, ifosfamide, etoposide, methotrexate, cisplatin and cytosine arabinoside. Locally, hyperfractionated radiotherapy was delivered at a total dose of 63.8 Gy (1.1 Gy twice daily, 10 fractions per week). After a median observation time of 11.8 (range 4-23) months from diagnosis three children are alive and without evidence of tumor progression. Two patients died from tumor progression 11 and 16 months respectively after initiation of therapy.
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Brain Neoplasms - diagnosis
Child - diagnosis
Child, Preschool - diagnosis
Combined Modality Therapy - diagnosis
Cytarabine - administration and dosage
Female - administration and dosage
Follow-Up Studies - administration and dosage
Humans - administration and dosage
Magnetic Resonance Imaging - administration and dosage
Male - administration and dosage
Methotrexate - administration and dosage
Pons - administration and dosage
Radiodermatitis - etiology
Radiotherapy Dosage - etiology
Remission Induction - etiology
Survival Rate - etiology
Thalamus - etiology

Find related publications in this database (Keywords)
Brain Stem Tumors
Hyperfractionated Radiotherapy
Sequential Chemoradiotherapy
Polychemotherapy
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