Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Pakisch, B; Urban, C; Slavc, I; Poier, E; Stücklschweiger, G; Oberbauer, R; Mokry, M; Poschauko, J; Hammer, J; Leitner, H.
Hyperfractionated radiotherapy and polychemotherapy in brain stem tumors in children.
Childs Nerv Syst. 1992; 8(4):215-218
Doi: 10.1007/BF00262849
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- Co-Autor*innen der Med Uni Graz
- Hackl Arnulf
- Mokry Michael
- Urban Ernst-Christian
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- Abstract:
- Between October 1989 and January 1991 five children with brain stem tumors were treated with sequential chemo- and radiotherapy. The polychemotherapy consisted of procarbazine, ifosfamide, etoposide, methotrexate, cisplatin and cytosine arabinoside. Locally, hyperfractionated radiotherapy was delivered at a total dose of 63.8 Gy (1.1 Gy twice daily, 10 fractions per week). After a median observation time of 11.8 (range 4-23) months from diagnosis three children are alive and without evidence of tumor progression. Two patients died from tumor progression 11 and 16 months respectively after initiation of therapy.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Antineoplastic Combined Chemotherapy Protocols - adverse effects
- Brain Neoplasms - diagnosis
- Child - diagnosis
- Child, Preschool - diagnosis
- Combined Modality Therapy - diagnosis
- Cytarabine - administration and dosage
- Female - administration and dosage
- Follow-Up Studies - administration and dosage
- Humans - administration and dosage
- Magnetic Resonance Imaging - administration and dosage
- Male - administration and dosage
- Methotrexate - administration and dosage
- Pons - administration and dosage
- Radiodermatitis - etiology
- Radiotherapy Dosage - etiology
- Remission Induction - etiology
- Survival Rate - etiology
- Thalamus - etiology
- Find related publications in this database (Keywords)
- Brain Stem Tumors
- Hyperfractionated Radiotherapy
- Sequential Chemoradiotherapy
- Polychemotherapy