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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Stockner, H; Schwingenschuh, P; Djamshidian, A; Silveira-Moriyama, L; Katschnig, P; Seppi, K; Dickson, J; Edwards, MJ; Lees, AJ; Poewe, W; Bhatia, KP; .
Is transcranial sonography useful to distinguish scans without evidence of dopaminergic deficit patients from Parkinson's disease?.
Mov Disord. 2012; 27(9):1182-1185
Doi: 10.1002/mds.25102
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- Co-authors Med Uni Graz
- Katschnig-Winter Petra
- Schwingenschuh Petra
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- Abstract:
- Background: Approximately 10% of patients clinically diagnosed with early Parkinson's disease (PD) subsequently have normal dopaminergic functional imaging. Transcranial sonography (TCS) has been shown to detect midbrain hyperechogenicity in approximately 90% of Parkinson's disease (PD) patients and 10% of the healthy population. The aim of this study was to investigate the prevalence of midbrain hyperechogenicity in patients with suspected parkinsonism and scans without evidence of dopaminergic deficit (SWEDD), in comparison to PD patients. Methods: TCS was performed in 14 patients with SWEDD and 19 PD patients. Results: There was a significantly increased area of echogenicity in the PD group (0.24 +/- 0.06 cm2), compared to the group of patients with SWEDD (0.13 +/- 0.06 cm2; P < 0.001). One (9.1%) of these patients, compared to 14 (82.5%) of the PD patients, was found to have hyperechogenicity (P < 0.001). Conclusions: We conclude that TCS is useful to distinguish PD patients from patients with suspected parkinsonism and SWEDD. (c) 2012 Movement Disorder Society
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Cognition Disorders - complications
- Diagnosis, Differential -
- Dopamine - metabolism
- Female -
- Humans -
- Magnetic Resonance Imaging -
- Male -
- Mesencephalon - radionuclide imaging
- Middle Aged -
- Nerve Fibers, Myelinated -
- Neuropsychological Tests -
- Parkinson Disease - physiopathology
- Positron-Emission Tomography -
- Temporal Bone - ultrasonography
- Ultrasonography, Doppler, Transcranial - methods
- Find related publications in this database (Keywords)
- transcranial sonography
- SWEDD
- Parkinson's disease
- hyperechogenicity