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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Neubauer, H; Platzer, I; Mueller, VR; Meyer, T; Liese, J; Koestler, H; Hahn, D; Beer, M.
Diffusion-weighted MRI of abscess formations in children and young adults.
World J Pediatr. 2012; 8(3):229-234
Doi: 10.1007/s12519-012-0362-4
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Beer Meinrad
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- Abstract:
- Diffusion-weighted MRI (DWI) is helpful for detection of brain abscess and pelvic abscess in adults. In the present study, we evaluated the diagnostic performance of DWI in children and young adults with abdominal and soft tissue abscess formations. Seventeen patients (11 females, aged 13 +/- 6 years) with suspected abdominal or soft-tissue abscess underwent routine MRI including free-breathing DWI and contrast-enhanced T1w imaging. Seventeen random age-matched patients with non-purulent abdominal fluid collections served as controls. Mean apparent diffusion coefficent (ADC) was measured for abscess, muscle, liver, spleen and kidney tissue as well as for cerebrospinal fluid, urine and free abdominal fluid. All fluid collections were identified on diffusion-weighted images. Thirteen of 14 confirmed abscess formations showed an ADC < 1.0 x 10(-3) mm(2)/s with a mean value of 0.80 +/- 0.38 mm(2)/s. One tuberculous softtissue abscess had a higher ADC of 1.85 x 10(-3) mm(2)/s. Ring enhancement on T1w imaging was seen in three nonpurulent fluid collections. There were no false-positive findings in the control group. Diffusion-weighted MRI is highly sensitive for abscess and may add specificity to contrast-enhanced T1w imaging of ring-enhancing fluid collections. DWI with free-breathing rapid image acquisition and without the need of intravenous contrast application constitutes a particularly useful choice in pediatric imaging.
- Find related publications in this database (using NLM MeSH Indexing)
- Abscess - diagnosis
- Adolescent -
- Child -
- Child, Preschool -
- Contrast Media - diagnostic use
- Diagnosis, Differential -
- Diffusion Magnetic Resonance Imaging - methods
- Female -
- Humans -
- Infant -
- Male -
- ROC Curve -
- Statistics, Nonparametric -
- Young Adult -
- Find related publications in this database (Keywords)
- abscess
- contrast medium
- diffusion-weighted imaging
- magnetic resonance imaging
- pediatric