Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Schneider, NI; Zigeuner, R; Langner, C.
Small Cell Carcinoma of the Urinary Bladder: A Rare Tumor with Propensity for Hepatic Involvement.
Am J Med Sci. 2013; 345(2):155-157
Doi: 10.1097/MAJ.0b013e3182648759
(- Case Report)
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Langner Cord
- Co-Autor*innen der Med Uni Graz
- Zigeuner Richard
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- Abstract:
- Small cell (neuroendocrine) carcinoma of the bladder is a rare entity, accounting for less than 1% of all bladder tumors. The authors report 2 new cases of the disease, both presenting with liver metastasis. In the first case, small cell carcinoma occurred in an 85-year-old woman as tumor recurrence of previous micropapillary carcinoma and urothelial carcinoma in situ, illustrating the common coexistence with conventional urothelial carcinoma. In the second case of a 58-year-old man, non-small cell tumor components were not observed. Accurate diagnosis of small cell carcinoma may be challenging. A panel of different antibodies, including neuron-specific enolase, chromogranin A, synaptophysin and CD56 (neural cell adhesion molecule) is recommended. In conclusion, small cell carcinoma represents a rare and aggressive form of bladder malignancy. As illustrated by the 2 cases and according to the literature review, the tumor shows a so far underrecognized propensity for hepatic involvement.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged, 80 and over -
- Carcinoma, Small Cell - diagnosis Carcinoma, Small Cell - therapy
- Female -
- Humans -
- Liver Neoplasms - diagnosis Liver Neoplasms - secondary Liver Neoplasms - therapy
- Male -
- Middle Aged -
- Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - therapy
- Find related publications in this database (Keywords)
- Small cell carcinoma
- Urinary bladder
- Liver metastasis
- Neuroendocrine
- Biomarker