Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Floery, D; Helbich, TH; Riedl, CC; Jaromi, S; Weber, M; Leodolter, S; Fuchsjaeger, MH.
Characterization of benign and malignant breast lesions with computed tomography laser mammography (CTLM) - Initial experience
INVEST RADIOL. 2005; 40(6): 328-335.
Doi: 10.1097/01.rli.0000164487.60548.28
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Fuchsjäger Michael
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Objectives: The aim of this study was to characterize benign and malignant breast lesions with computed tomography-laser mammography (CTLM). Materials and Methods: In a prospective study, 100 female patients with 105 breast lesions classified as BIRADS IV to V at mammography underwent mammography, CTLM, and histologic verification at our institution. CTLM images were analyzed by radiologists with knowledge of the lesion's position but who were blinded to histology and morphologic findings from mammography. Two radiologists independently evaluated whether there was increased absorption, a sign of malignancy, on CTLM and assessed the appearance (volumes or linear branching) and shape (round or irregular) of the lesions. Results: Histologic analysis revealed 55 benign (52.4%) and 50 malignant (47.6%) breast lesions. Increased absorption was observed significantly more often in malignant than in benign lesions (70.0% vs. 32.7%, P = 0.028). Invasive cancer showed increased absorption in 76.2%, and ductal carcinoma in situ in 37.5%. Common morphologic characteristics of increased absorption were "volumes" (85.7% of malignant and 77.8% of benign lesions) with round shape (78.1% of malignant and 73.3% of benign lesions). Conclusion: Our data indicate that CTLM, when used as an adjunct to mammography, may provide additional information to characterize benign and malignant breast lesions.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Aged -
- Aged, 80 and over -
- Breast Diseases - radiography
- Breast Neoplasms - radiography
- Carcinoma in Situ - radiography
- Carcinoma, Ductal - radiography
- Female -
- Humans -
- Lasers -
- Mammography - methods
- Middle Aged -
- Prospective Studies -
- Tomography, X-Ray Computed -
- Find related publications in this database (Keywords)
- breast neoplasms
- mammography
- computed tomography-laser mammography
- optical imaging
- laser technique