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Fuchsjager, MH; Helbich, TH; Ringl, H; Funovics, MA; Rudas, M; Riedl, C; Pfarl, G.
Electrical impedance scanning in the differentiation of suspicious breast lesions: Comparison with mammography, ultrasound and histopathology
Rofo. 2002; 174(12):1522-1529 Doi: 10.1055/s-2002-35941
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Leading authors Med Uni Graz: Fuchsjäger Michael
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Abstract:: Purpose: To assess the value of Electrical Impedance Scanning (EIS) in the differentiation of suspicious breast lesions in comparison to mammography (MG) and ultrasound (US). Methods: In 95 female patients (median 53.1 ys) 95 suspicious breast lesions (BI-RADS(TM) III - V) in MG or US underwent targeted EIS (TransScan TS 2000((R)); TransScan Medical, Israel; Siemens Elema, Sweden). Histopathologic proof (vacuum-assisted biopsy or surgical biopsy) was obtained in all cases. MG, US and EIS were independently assessed by two radiologists in consensus. Chi-square tests as well as variance-analysis for ROC-statistics were performed. Results: Of 95 lesions, 44 were benign, 51 malignant. Sensitivity, specificity, positive and negative predictive values were, respectively for MG 95.3%, 23.5%, 51.3% and 85.7%, for US 86.5%, 44.2%, 57.1% and 79.1%, for EIS 77.3%, 82.3%, 79.1% and 80.8%. The ROC-analysis revealed a significant greater area under the curve for EIS than for MG and US. The sensitivity for EIS was higher in lesions < 10 mm (n = 26; 100%) and in invasive cancers (n = 31; 80.6%). The negative predictive value of EIS was higher in BI-RADS(TM)-IV-Iesions (83.9%) as well as in dense breast parenchyma on the mammogram (86.7%). Conclusion: EIS shows potential adjunctive value to MG and US in the differentiation of suspicious breast lesions.
Find related publications in this database (using NLM MeSH Indexing): Adult -; Aged -; Biopsy -; Breast - pathology; Breast Diseases - diagnosis Breast Diseases - pathology Breast Diseases - radiography; Breast Neoplasms - diagnosis Breast Neoplasms - pathology Breast Neoplasms - radiography; Carcinoma in Situ - diagnosis Carcinoma in Situ - pathology Carcinoma in Situ - radiography; Carcinoma, Ductal, Breast - diagnosis Carcinoma, Ductal, Breast - pathology Carcinoma, Ductal, Breast - radiography; Carcinoma, Lobular - diagnosis Carcinoma, Lobular - pathology Carcinoma, Lobular - radiography; Chi-Square Distribution -; Diagnosis, Differential -; Electric Impedance - diagnostic use; Female -; Humans -; Mammography -; Middle Aged -; Predictive Value of Tests -; ROC Curve -; Sensitivity and Specificity -; Ultrasonography, Mammary -
Find related publications in this database (Keywords): breast neoplasms; electrical impedance scanning; breast radiography; ultrasound