Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Pabst, T; Sandstede, J; Beer, M; Kenn, W; Neubauer, S; Hahn, D.
Sodium T-2* relaxation times in human heart muscle
J Magn Reson Imaging. 2002; 15(2):215-218
Doi: 10.1002/jmri.10046
Web of Science
PubMed
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- Co-Autor*innen der Med Uni Graz
- Beer Meinrad
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- Abstract:
- Purpose: To determine sodium transverse relaxation (T-2*) characteristics for myocardium, blood and cartilage in humans. Methods: T-2* measurements were performed using a 3D ECG-gated spoiled gradient echo sequence. A 1.5 Tesla clinical scanner and a Na-23 heart surface coil were used to examine eight healthy volunteers. In biological tissue, the sodium 23 nucleus exhibits a two-component T-2 relaxation due to the spin 3/2 and its quadrupolar nature. The long T-2* components of normal myocardium, blood, and cartilage were quantified. For myocardium, the T-2* was determined separately for the septum, anterior wall, lateral wall, and posterior wall. Results: The long T-2* relaxation time components of 13.3 +/- 4.3 msec (septum 13.9 +/- 3.2 msec, anterior wall 13.8 +/- 5.4 msec, lateral wall 11.4 +/- 4.1 msec, posterior wall 14.1 +/- 3.7 msec), 19.3 +/- 3.3 msec, and 10.2 +/- 1.6 msec, were significantly different for myocardium, blood, and cartilage, respectively (P < 0.00001, Friedman's ANOVA), Conclusion: Measurement of Na-23 T-2* relaxation times is feasible for different regions of the human heart muscle, which might be useful for the evaluation of cardiac pathologies.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Blood - metabolism
- Cartilage - metabolism
- Electrocardiography -
- Female -
- Humans -
- Magnetic Resonance Imaging - methods
- Male -
- Myocardium - metabolism
- Signal Processing, Computer-Assisted -
- Sodium - metabolism
- Find related publications in this database (Keywords)
- magnetic resonance imaging
- sodium imaging
- T-2* relaxation time
- heart