Selected Publication:
Sandstede, J; Lipke, C; Beer, M; Kenn, W; Pabst, T; Neubauer, S; Hahn, D.
Delayed enhancement after injection of Gd-DTPA in dysfunctional myocardium correlation with regional wall motion improvement after revascularization
Radiologe. 2000; 40(2):150-154
Doi: 10.1007/s001170050024
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
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Beer Meinrad
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- Abstract:
- Purpose: The aim of the study was to correlate delayed contrast enhancement of dysfunctional regions of the myocardium after injection of Gd-DTPA with the improvement of regional contractility 3 months after revascularization. Material and methods: Eleven patients with coronary artery disease and wall motion abnormalities underwent MR imaging before and 3 months after revascularization therapy (PTCA or CABG). Short-axis images were acquired using a cine gradient echo sequence. After revascularization, a representative slice was analyzed 14+/-1 min after injection of 0.1 mmol/kg Gd-DTPA using a T1-weighted turbo fast low-angle shot sequence. Improved systolic wall thickening 3 months after revascularization served as criterion of viability and was correlated with delayed contrast enhancement patterns. Results: After revascularization, 6 patients showed complete recovery of the dysfunctional area, 1 patient partial recovery,and 4 patients remained unchanged. All 4 patients with persisting wall motion abnormalities, 1/6 patients with recovery and the patient with partial recovery revealed a delayed enhancement Conclusions: Three months after revascularization, delayed enhancement of dysfunctional myocardium is evident in patients without regional wall motion improvement, while the lack of delayed enhancement correlates with improvement of regional contractility.
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Adult -
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Aged -
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Contrast Media -
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Diastole - physiology
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Female -
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Follow-Up Studies -
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Gadolinium DTPA - diagnostic use
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Humans -
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Image Enhancement -
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Magnetic Resonance Imaging -
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Male -
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Middle Aged -
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Myocardial Contraction - physiology
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Myocardial Infarction - diagnosis Myocardial Infarction - physiopathology Myocardial Infarction - therapy
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Myocardial Revascularization -
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Myocardial Stunning - diagnosis Myocardial Stunning - physiopathology
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Sensitivity and Specificity -
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Systole - physiology
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Treatment Outcome -
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Ventricular Dysfunction, Left - diagnosis Ventricular Dysfunction, Left - physiopathology
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heart
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MR
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myocardial infarction
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myocardial viability
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Gd-DTPA-delayed enhancement