Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Sandstede, JJW; Pabst, T; Beer, M; Lipke, C; Baurle, K; Butter, F; Harre, K; Kenn, W; Voelker, W; Neubauer, S; Hahn, D.
Assessment of myocardial infarction in humans with Na-23 MR imaging: Comparison with cine MR imaging and delayed contrast enhancement
Radiology. 2001; 221(1):222-228
Doi: 10.1148/radiol.2211001563
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- Co-Autor*innen der Med Uni Graz
- Beer Meinrad
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- Abstract:
- PURPOSE: To demonstrate the feasibility of sodium 23 (Na-23) magnetic resonance (MR) imaging for assessment of subacute and chronic myocardial infarction and compare with cine, late enhancement, and T2-weighted imaging. MATERIALS AND METHODS: Thirty patients underwent MR imaging 8 days +/- 4 (subacute, n = 15) or more than 6 months (chronic, n = 15) after myocardial infarction by using a Na-23 surface coil with a double angulated electrocardiogram-triggered three-dimensional gradient-echo sequence at 1.5 T. In addition, cine, inversion-recovery gradient-echo, and, in the subacute group, T2-weighted images (n = 9) were obtained. Myocardial infarction mass was depicted as elevated signal intensity or wall motion abnormalities and expressed as a percentage of total left ventricular mass for all modalities. Correlations were tested with correlation coefficients. RESULTS: All patients after subacute infarction and 12 of 15 patients with chronic infarction had an area of elevated Na-23 signal intensity that significantly correlated with wall motion abnormalities (subacute; r = 0.96, P < .001, and chronic; r = 0.9, P < .001); three patients had no wall motion abnormalities or elevated Na-23 signal intensity. Only 10 patients in the subacute and nine in the chronic group revealed late enhancement; significant correlation with Na-23 MR imaging occurred only in subacute group (r = 0.68, P < .05). Myocardial edema in subacute infarction correlated (r = 0.71, P < .05) with areas of elevated Na-23 signal intensity but was extensively larger. CONCLUSION : Na-23 MR imaging demonstrates dysfunctional myocardium caused by subacute and chronic myocardial infarction.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Aged, 80 and over -
- Chronic Disease -
- Feasibility Studies -
- Female -
- Humans -
- Image Enhancement -
- Magnetic Resonance Imaging - methods
- Male -
- Middle Aged -
- Myocardial Infarction - pathology
- Sodium - diagnostic use
- Time Factors -
- Find related publications in this database (Keywords)
- myocardium, infarction
- myocardium, MR
- magnetic resonance (MR), sodium studies