Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Spindler, M; Schmidt, M; Geier, O; Sandstede, J; Hahn, D; Ertl, G; Beer, M.
Functional and metabolic recovery of the right ventricle during Bosentan therapy in idiopathic pulmonary arterial hypertension
J Cardiovasc Magn Reson. 2005; 7(5):853-854
Doi: 10.1080/10976640500295540
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- Abstract:
- An impaired high-energy phosphate metabolism might play a critical role in the pathogenesis of right ventricular (RV) failure due to chronic pulmonary arterial hypertension (PAH). 31P-NMR spectroscopy is well established for measurements of high-energy phosphate metabolites in various left ventricular heart diseases, however, mainly for technical and sensitivity reasons, its successful transfer for measurements in the RV is currently missing. In the present study, the usefulness of this non-invasive approach is not only shown in RV failure due to PAH but also tested during subsequent therapy.
- Find related publications in this database (using NLM MeSH Indexing)
- Antihypertensive Agents - therapeutic use
- Humans -
- Hypertension, Pulmonary - complications Hypertension, Pulmonary - diagnosis Hypertension, Pulmonary - drug therapy Hypertension, Pulmonary - metabolism Hypertension, Pulmonary - physiopathology
- Magnetic Resonance Spectroscopy -
- Male -
- Middle Aged -
- Phosphates - metabolism
- Pulmonary Wedge Pressure - drug effects
- Stroke Volume - drug effects
- Sulfonamides - therapeutic use
- Ventricular Dysfunction, Right - diagnosis Ventricular Dysfunction, Right - drug therapy Ventricular Dysfunction, Right - etiology Ventricular Dysfunction, Right - metabolism Ventricular Dysfunction, Right - physiopathology
- Ventricular Function, Right - drug effects
- Find related publications in this database (Keywords)
- pulmonary hypertension
- magnetic resonance spectroscopy
- right ventricular function
- myocardial metabolisin