Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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SHR Neuro Krebs Kardio Lipid Stoffw Microb
de la Cruz, GG; Groschner, K; Kappe, CO; Glasnov, TN; .
High-speed microwave assisted synthesis of SEA0400-a selective inhibitor of the Na+/Ca2+ exchanger.
TETRAHEDRON LETT. 2012; 53(29): 3731-3734.
Doi: 10.1016/j.tetlet.2012.04.120
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- Co-Autor*innen der Med Uni Graz
- Groschner Klaus
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- Abstract:
- An efficient and rapid five-step synthesis of SEA0400, a selective Na+/Ca2+ exchanger (NCX) inhibitor, using controlled microwave heating is reported. In addition, a novel three-step route omitting the key Baeyer Villiger oxidation/hydrolysis sequence has been developed. (C) 2012 Elsevier Ltd. All rights reserved.
- Find related publications in this database (Keywords)
- Baeyer-Villiger oxidation
- Williamson ether synthesis
- Microwave-assisted synthesis
- Continuous-flow hydrogenation
- Process intensification
- SEA0400