Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Koestenberger, M; Nagel, B; Ravekes, W; Avian, A; Heinzl, B; Fritsch, P; Fandl, A; Rehak, T; Gamillscheg, A.
Left ventricular long-axis function: Reference values of the mitral annular plane systolic excursion in 558 healthy children and calculation of z-score values.
Am Heart J. 2012; 164(1):125-131
Doi: 10.1016/j.ahj.2012.05.004
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Koestenberger Martin
- Co-Autor*innen der Med Uni Graz
- Avian Alexander
- Fritsch Peter
- Gamillscheg Andreas
- Nagel Bert Hermann Philipp
- Rehak Thomas
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- Abstract:
- Background Longitudinal myocardial function has gained more interest in the last years. The mitral annular plane systolic excursion (MAPSE) is an echocardiographic measurement to assess left ventricular (LV) long-axis function in adults. The aim of this study was to evaluate MAPSE values in a healthy pediatric population and to propose reference values. Methods A prospective study was conducted in a group of 558 healthy children and adolescents (age day 1 to 18 years) (body surface area [BSA] 0.18-2.21 m(2)). We determined the effects of age and BSA on MAPSE values and a possible correlation of MAPSE values with LV ejection fraction values. Results The MAPSE ranged from a mean of 0.57 cm (z-score +/- 2: 0.38-0.76 cm) in neonates to 1.63 cm (z-score +/- 2: 1.31-1.95 cm) in 18-year-old adolescents. The MAPSE values showed a positive correlation with age (r = 0.87, P < .001) and BSA (r = 0.89, P < .001) with a nonlinear course. There was no significant difference in MAPSE values between females or males. A positive correlation was found between MAPSE values and LV ejection fraction values (r = 0.28, P < .001). Conclusions Z-scores of MAPSE values were calculated, and percentile charts were established to serve as reference data in patients with congenital heart disease or heart failure in the future. (Am Heart J 2012;164:125-31.)
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Child -
- Child, Preschool -
- Female -
- Humans -
- Infant -
- Infant, Newborn -
- Male -
- Mitral Valve - physiology
- Prospective Studies -
- Reference Values -
- Systole -
- Ventricular Function, Left -