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SHR Neuro Cancer Cardio Lipid Metab Microb
Reiter, U; Reiter, G; Wagner, T; Kozma, N; Roland, J; Schöllnast, H; Ebner, F; Lanzer, G.
Four-dimensional temperature distributions in red blood cells withdrawn from storage and exposed to ambient temperature: a magnetic resonance thermometry study.
Transfusion. 2013; 53(1):167-173
Doi: 10.1111/j.1537-2995.2012.03798.x
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Reiter Ursula
- Co-authors Med Uni Graz
- Ebner Franz
- Kozma Noemi
- Lanzer Gerhard
- Schoellnast Helmut
- Wagner Thomas
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- Abstract:
- BACKGROUND: Recommended by current guidelines, red blood cell (RBC) temperature should not exceed 10 degrees C during transport. Since warming is a generically three-dimensional process that is not homogeneous, it is necessary to clarify the term temperature during warming. The purpose of this study was therefore to investigate laws and relations between surface, mean, and core temperature and the corresponding times when they exceed 10 degrees C during warm-up. STUDY DESIGN AND METHODS: Time-resolved three-dimensional temperature distributions of 53 resuspended RBC units (mean volume, 253 +/- 17 mL) were measured noninvasively by magnetic resonance thermometry. Warm-up temperature maps were visualized and analyzed by dedicated software. RESULTS: Mean times when surface, mean, and core temperature exceeded 10 degrees C were 16 +/- 4, 24 +/- 5, and 36 +/- 7 minutes, respectively. Times strongly correlated with each other (r = 0.78-0.95) and their variances mainly depended on RBC storage temperature and RBC pouch width (R2 = 0.81-0.89). Measured mean temperature time courses were well described by a lumped capacitive model of heat transfer with a sample width-dependent time constant tRBC = 56.3 +/- 3.5 minutes (mean R2 = 0.996). CONCLUSION: Times when RBC surface, mean, and core temperature exceed 10 degrees C can be estimated from each other. Moreover RBC mean temperature can be calculated for arbitrary storage and ambient temperatures. Findings might serve as a helpful tool in RBC temperature monitoring.
- Find related publications in this database (using NLM MeSH Indexing)
- Blood Preservation - methods
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- Erythrocytes - cytology Erythrocytes - metabolism
- Humans -
- Software -
- Temperature -