Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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SHR Neuro Krebs Kardio Lipid Stoffw Microb
Hammerer, PG; Augustin, H; Blonski, J; Graefen, M; Haese, A; Erbersdobler, A; Daghofer, F; Huland, H.
Influence of transrectal endosonography on the clinical staging of impalpable prostate cancer. A controversy over the TNM system
UROLOGE A. 2004; 43(3): 307-312.
Doi: 10.1007/s00120-004-0531-8
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- Co-Autor*innen der Med Uni Graz
- Augustin Herbert
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- Abstract:
- Since 1992, the TNM system has classified impalpable prostate cancers with visible lesions on imaging as clinical stage T2. Due to controversial reports in the literature,this classification has not been well accepted in clinical practice. Most urologists consider all impalpable prostate cancers irrespective of their imaging as T1c. Transrectal ultrasound (TRUS) is the imaging tool most frequently used for diagnostic purposes in prostatic diseases. In our study, we compared prognostic cancer characteristics and the likelihood of biochemical cure between impalpable tumors invisible on TRUS and those visible. Identical comparisons were performed between impalpable, but visible prostate cancers and palpable T2a tumors. Patients with impalpable and invisible prostate cancers showed the most favorable cancer characteristics. Impalpable, but visible prostate cancers differed in their prognostic parameters from those invisible. These differences were more pronounced when compared to palpable T2a tumors. The probability of biochemical cure was comparable in both groups of impalpable cancers. However, impalpable tumors visible on TRUS exhibited a significantly more favorable outcome than T2a cancers. Consequently, impalpable prostate cancers should be classified as T1c regardless of their visibility on TRUS.
- Find related publications in this database (using NLM MeSH Indexing)
- Endosonography - methods
- Germany - epidemiology
- Humans - epidemiology
- Male - epidemiology
- Middle Aged - epidemiology
- Neoplasm Staging - methods
- Palpation - methods
- Prostatic Neoplasms - diagnosis
- Reproducibility of Results - diagnosis
- Sensitivity and Specificity - diagnosis
- Find related publications in this database (Keywords)
- prostate cancer
- radical prostatectomy
- prognosis
- transrectal ultrasound
- TNM