Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ebner, T; Tews, G; Sommergruber, M; Moser, M.
Cytoplasmic pitting has a negative influence on implantation outcome.
J Assist Reprod Genet. 2005; 22(6):239-244
Doi: 10.1007/s10815-005-5146-5
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- Führende Autor*innen der Med Uni Graz
- Ebner Thomas
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- Abstract:
- Purpose: Since cytoplasmic pitting is a morphological phenomenon discussed controversially, this study was set up in order to assess the actual influence of cytoplasmic pitting on treatment outcome. Methods: Four hundred and one patients undergoing 484 consecutive treatment cycles were evaluated retrospectively in order to assess the actual influence of pitting on treatment outcome. Results: Pitting was found to be reduced in single culture as compared to group culture (p < 0.01). No correlation of cytoplasmic texture with rates of implantation and pregnancy could be observed, but a significantly higher proportion (p < 0.05) of gestational sacs vanished in the group with exclusive transfer of pitted embryos compared to the unaffected group. Obstetric and perinatal outcome was not affected. Conclusions: It is possible that culture conditions favor cytoplasmic pitting, a morphological phenomenon which, in the extreme case, may result in early loss of gestation sacs.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Culture Techniques -
- Cytoplasm - pathology
- Embryo Implantation -
- Embryonic Development -
- Female -
- Fertilization in Vitro -
- Humans -
- Infertility, Female - therapy
- Pregnancy -
- Pregnancy Outcome -
- Retrospective Studies -
- Treatment Outcome -
- Find related publications in this database (Keywords)
- cytoplasmic pitting
- clinical pregnancy rate
- culture conditions
- early pregnancy loss
- implantation rate