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SHR Neuro Cancer Cardio Lipid Metab Microb

Pistracher, K; Gellner, V; Riegler, S; Schökler, B; Scarpatetti, M; Kurschel, S.
Cerebral haemorrhage in the presence of primary childhood central nervous system vasculitis-a review.
Childs Nerv Syst. 2012; 28(8):1141-1148 Doi: 10.1007/s00381-012-1827-4
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Leading authors Med Uni Graz
Kurschel-Lackner Senta
Pistracher Karin Felicitas
Co-authors Med Uni Graz
Gellner Verena
Riegler Stefan
Scarpatetti Michael
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Abstract:
The aim of the study was to evaluate frequency and clinical relevance of haemorrhagic events associated with primary angiitis of the central nervous system in childhood (cPACNS), a rare but increasingly recognized disease with varying clinical presentations. A systematic literature review from 1990 onwards was conducted to identify reported cases of cPACNS. A total of 110 paediatric patients met the inclusion criteria. The median age was 9.5 years. Seven children (7/110, 6.4 %) demonstrated cerebral haemorrhage. Death occurred only in children with cerebral haemorrhage (4/110, 3.6 %); both a sudden and prolonged course of disease was observed. PACNS is a rare disease and the occurrence of haemorrhage with this condition is even rarer; however, the risk of an unfavourable outcome under these circumstances seems to be increased. PACNS adds to the list of differential diagnoses of intracerebral haemorrhage in the paediatric population.
Find related publications in this database (using NLM MeSH Indexing)
Cerebral Hemorrhage - epidemiology Cerebral Hemorrhage - etiology Cerebral Hemorrhage - therapy
Child -
Humans -
Risk Factors -
Treatment Outcome -
Vasculitis, Central Nervous System - complications

Find related publications in this database (Keywords)
Haemorrhage
Central nervous system vasculitis
Angiitis
Small vessel disease
Paediatrics
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