Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Paar, C; Palmetshofer, C; Flieger, K; Geit, M; Kaiser, R; Stekel, H; Berg, J.
Genotypic antiretroviral resistance testing for human immunodeficiency virus type 1 integrase inhibitors by use of the TruGene sequencing system.
J Clin Microbiol. 2008; 46(12):4087-4090
Doi: 10.1128/JCM.01246-08
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- Berg Jörg
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- Abstract:
- A sequencing assay for detection of mutations conferring resistance to human immunodeficiency virus type 1 (HIV-1) integrase inhibitors raltegravir and elvitegravir was developed using the automated TruGene sequencing system. The assay returned clear sequencing results for samples with >or=500 RNA copies/ml for mutation detection and HIV-1 subtyping across a spectrum of HIV-1 subtypes.
- Find related publications in this database (using NLM MeSH Indexing)
- Amino Acid Substitution - genetics
- Genotype -
- HIV-1 - drug effects HIV-1 - genetics
- Humans -
- Integrase Inhibitors - pharmacology
- Microbial Sensitivity Tests - methods
- Mutation, Missense -
- RNA, Viral - genetics
- Sequence Analysis, DNA - methods