Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Frühwirth, M; Fischer, H; Simma, B; Hochleitner, B; Königsrainer, A; Margreiter, R; Ellemunter, H.
Rotavirus infection as cause of tacrolimus elevation in solid-organ-transplanted children.
Pediatr Transplant. 2001; 5(2):88-92
Doi: 10.1034/j.1399-3046.2001.005002088.x
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Hager Boris
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- Rotavirus (RV) is the most common cause of diarrheal illness in children. We report three solid-organ-transplanted patients in whom RV infection caused increased trough levels of the immunosuppressive macrolide tacrolimus (TAC) by mechanisms that are still under investigation. The virus was detected for longer in the feces of these patients than in infants not receiving immunosuppressive therapy. In association with short-term monitoring of blood trough levels of TAC, the dosage should be reduced early if symptoms of an acute gastroenteritis are present.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Child -
- Diarrhea - blood Diarrhea - virology
- Drug Monitoring -
- Feces - virology
- Female -
- Gastroenteritis - blood Gastroenteritis - virology
- Humans -
- Immunosuppressive Agents - administration and dosage Immunosuppressive Agents - blood
- Infant -
- Kidney Transplantation -
- Liver Transplantation -
- Lung Transplantation -
- Male -
- Postoperative Complications - blood
- Rotavirus Infections - blood
- Tacrolimus - administration and dosage Tacrolimus - blood
- Transplantation -
- Find related publications in this database (Keywords)
- rotavirus
- gastroenteritis
- tacrolimus