Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Koestenberger, M; Nagel, B; Avian, A; Ravekes, W; Sorantin, E; Cvirn, G; Beran, E; Halb, V; Gamillscheg, A.
Systolic Right Ventricular Function in Children and Young Adults with Pulmonary Artery Hypertension Secondary to Congenital Heart Disease and Tetralogy of Fallot: Tricuspid Annular Plane Systolic Excursion (TAPSE) and Magnetic Resonance Imaging Data.
Congenit Heart Dis. 2012; 7(3):250-258
Doi: 10.1111/j.1747-0803.2012.00655.x
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Koestenberger Martin
- Co-Autor*innen der Med Uni Graz
- Avian Alexander
- Beran Elisabeth
- Cvirn Gerhard
- Gamillscheg Andreas
- Nagel Bert Hermann Philipp
- Sorantin Erich
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- Abstract:
- Objective. The tricuspid annular plane systolic excursion (TAPSE), as echocardiographic index to assess right ventricular (RV) systolic function, has not been investigated thoroughly in children and young adults with tetralogy of Fallot (TOF) and pulmonary artery hypertension secondary to congenital heart disease (PAH-CHD). Patients. TAPSE values of 49 patients with PAH-CHD and 156 patients with TOF were compared with age-matched normal subjects. TAPSE values were also compared with RV ejection fraction (RVEF) and RV indexed end-diastolic volume (RVEDVi) determined by magnetic resonance imaging in PAH-CHD and TOF patients. Results. Patients with a PAH-CHD showed a positive correlation between TAPSE with RVEF (r= 0.81; P < 0.001) and a negative correlation between TAPSE with RVEDVi (r=-0.67; P < 0.001). Similarly, in our TOF patients, a positive correlation between TAPSE with RVEF (r= 0.65; P < 0.001) and a negative correlation between TAPSE with RVEDVi (r=-0.42; P < 0.001) was seen. Conclusions. Significant pressure overload in PAH-CHD patients and volume overload in TOF patients lead to a decreased systolic RV function, determined by TAPSE and magnetic resonance imaging and to increased RVEDVi values, determined by MRI, with time.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Age Factors -
- Blood Pressure -
- Cardiac Catheterization -
- Case-Control Studies -
- Child -
- Child, Preschool -
- Cross-Sectional Studies -
- Echocardiography -
- Female -
- Heart Defects, Congenital - complications Heart Defects, Congenital - diagnosis Heart Defects, Congenital - physiopathology Heart Defects, Congenital - ultrasonography
- Humans -
- Hypertension, Pulmonary - diagnosis Hypertension, Pulmonary - etiology Hypertension, Pulmonary - physiopathology Hypertension, Pulmonary - ultrasonography
- Infant -
- Magnetic Resonance Imaging -
- Male -
- Observer Variation -
- Predictive Value of Tests -
- Reproducibility of Results -
- Stroke Volume -
- Tetralogy of Fallot - complications Tetralogy of Fallot - diagnosis Tetralogy of Fallot - physiopathology Tetralogy of Fallot - ultrasonography
- Tricuspid Valve - physiopathology Tricuspid Valve - ultrasonography
- Ventricular Dysfunction, Right - diagnosis Ventricular Dysfunction, Right - etiology Ventricular Dysfunction, Right - physiopathology Ventricular Dysfunction, Right - ultrasonography
- Ventricular Function, Right -
- Young Adult -
- Find related publications in this database (Keywords)
- Systolic Right Ventricular Function
- Volume Overload
- Pressure Overload
- Tricuspid Annular Plane Systolic Excursion