Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Cota, C; Ferrara, G; Cerroni, L.
Granuloma annulare with prominent lymphoid infiltrates ("pseudolymphomatous" granuloma annulare).
Am J Dermatopathol. 2012; 34(3):259-262
Doi: 10.1097/DAD.0b013e31822a2aca
(- Case Report)
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Cerroni Lorenzo
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- Abstract:
- Granuloma annulare (GA) is characterized histopathologically by 3 patterns: necrobiotic granuloma, interstitial incomplete form and, rarely, sarcoidal or tuberculoid granuloma. The amount of lymphoid infiltrate in GA is usually limited. We describe 10 cases of GA with prominent "pseudolymphomatous" lymphoid infiltrates mimicking cutaneous lymphoid hyperplasia. Patients were 6 males and 4 females (mean age 49.9 years, median age 47 years, age range 25-70). Lesions were localized to a limited area of the body (n = 6), or involved the entire trunk (n = 3), or were generalized (n = 1). The correct clinical diagnosis of GA was provided only in 30% of the cases. In all cases, histopathologic features were characterized by dense, nodular, superficial, and deep infiltrates of lymphocytes. Immunohistology revealed predominance of T lymphocytes in 7 of 7 tested cases. This "pseudolymphomatous" variant of GA represents a pitfall in the histopathologic diagnosis of the disease and may be misinterpreted as other types of cutaneous lymphoproliferative disorders.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Biopsy -
- Dermis - immunology
- Female -
- Granuloma Annulare - complications
- Humans -
- Lymphoid Tissue - pathology
- Male -
- Middle Aged -
- Pseudolymphoma - complications
- T-Lymphocytes - pathology
- Find related publications in this database (Keywords)
- granuloma annulare
- histopathologic variant
- pseudolymphoma