Medizinische Universität Graz - Research portal

Go directly to the nagivation.
Go directly to the content.

Navigation/Search

Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Moscarella, E; Argenziano, G; Longo, C; Cota, C; Ardigò, M; Stigliano, V; Mete, LS; Donati, P; Piana, S; Silipo, V; Catricalà, C; Albertini, G; Zalaudek, I.
Clinical, dermoscopic and reflectance confocal microscopy features of sebaceous neoplasms in Muir-Torre syndrome.
J Eur Acad Dermatol Venereol. 2013; 27(6):699-705 Doi: 10.1111/j.1468-3083.2012.04539.x
Web of Science PubMed FullText FullText_MUG

Co-authors Med Uni Graz: Zalaudek Iris
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: Background MuirTorre syndrome (MTS) is an autosomal-dominant disorder characterized by the association of sebaceous tumors or keratoacanthomas with an early onset visceral cancer in the spectrum of Lynch syndrome. Observations A total of 20 sebaceous tumors including 18 sebaceous adenoma and two sebaceomas of six patients with MTS were analysed. Two main clinico-dermoscopic features were observed: (1) clinically pink to white papules/nodules with a central crater, dermoscopically characterized by radially arranged, elongated crown vessels surrounding opaque structureless yellow areas at times covered by blood crusts (n=13) and (2), clinically pink to yellow papules/nodules without a central crater, dermoscopically exhibiting a few, loosely arranged yellow comedo-like globules and branching arborizing vessels (n=7). Confocal microscopy was available in three sebaceous adenomas and revealed a good histopathologic correlation; sebaceous lobules were composed by clusters of ovoid cells with dark nuclei and bright, highly refractile glistening cytoplasm. They were delimited by a rim of epithelial cells, corresponding to basaloid cells. Conclusions A better characterization of clinical, dermoscopic and confocal microscopy features of sebaceous tumors may improve their recognition and consequently, aid to rise the suspect for MTS.
Find related publications in this database (using NLM MeSH Indexing): Adenoma - complications; Aged -; Dermoscopy -; Female -; Humans -; Male -; Microscopy, Confocal -; Middle Aged -; Muir-Torre Syndrome - complications; Retrospective Studies -; Sebaceous Gland Neoplasms - complications