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Dasgupta, B; Cimmino, MA; Maradit-Kremers, H; Schmidt, WA; Schirmer, M; Salvarani, C; Bachta, A; Dejaco, C; Duftner, C; Jensen, HS; Duhaut, P; Por, G; Kaposi, NP; Mandl, P; Balint, PV; Schmidt, Z; Iagnocco, A; Nannini, C; Cantini, F; Macchioni, P; Pipitone, N; Amo, MD; Espgol-Frigol, G; Cid, MC; Martnez-Taboada, VM; Nordborg, E; Direskeneli, H; Aydin, SZ; Ahmed, K; Hazleman, B; Silverman, B; Pease, C; Wakefield, RJ; Luqmani, R; Abril, A; Michet, CJ; Marcus, R; Gonter, NJ; Maz, M; Carter, RE; Crowson, CS; Matteson, EL.
2012 provisional classification criteria for polymyalgia rheumatica: a European League Against Rheumatism/American College of Rheumatology collaborative initiative.
Ann Rheum Dis. 2012; 71(4): 484-492.
Doi: 10.1136/annrheumdis-2011-200329
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- Co-Autor*innen der Med Uni Graz
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Dejaco Christian
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- Abstract:
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The objective of this study was to develop EULAR/ACR classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of RF and/or ACPA (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness>45 minutes, elevated CRP and/or ESR and new hip pain. These criteria are not meant for diagnostic purposes.
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Age Factors -
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Aged -
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Aged, 80 and over -
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Algorithms -
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Arthritis, Rheumatoid - diagnosis
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Biological Markers - blood
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Blood Sedimentation -
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C-Reactive Protein - analysis
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Diagnosis, Differential -
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Female -
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Glucocorticoids - therapeutic use
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Hip Joint - physiopathology
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Humans -
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International Cooperation -
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Male -
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Middle Aged -
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Pain - etiology
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Polymyalgia Rheumatica - complications
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Prospective Studies -
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Range of Motion, Articular -
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Sensitivity and Specificity -
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Shoulder Pain - etiology